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John Shaw and Kiran Mazumdar-Shaw
Pharmaceuticals
Rank 2017
7=
Worth
£1,150m
Rise/fall
£530m

Mazumdar, 64, trained as a brewer before moving into a business developing enzymes used in food, which evolved into Bangalore biopharmaceutical firm Biocon. After it was sold to ICI in 1997 the Indian-born entrepreneur’s future husband, Glaswegian Shaw, arranged $2m finance to buy it back. The operation floated in 2004 and has risen strongly in the past year to be valued at £2.7bn, with the couple’s joint holding up from £593m to more than £1bn. They are company chairwoman and vice-chairman respectively. 

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